Radiotherapy

Textbooks

S. Webb. Contemporary IMRT: Developing Physics and Clinical Implementation. Institute of Physics Publishing, Bristol, 2004.

S.H. Levitt, J.A. Purdy, A.A. Perez and S. Vijayakumar (eds.). Technical Basis of Radiation Therapy: Practical Clinical Applications, 4^th ed. Springer, Berlin, Heidelberg, New York, 2006.

E.C. Halperin, C.A. Perez, and L.W. Brady (eds.). Perez and Brady’s Principles and Practice of Radiation Oncology. 5^th ed. Lippincott, Williams and Wilkins, Philadelphia, 2008.

Journal articles (peer reviewed literature)

S. Brockbank et al. Pretreatment Information on Dysphagia: Exploring the Views of Head and Neck Cancer Patients. Journal of Pain and Symptom Management 49, 89-97 (2015).

J. Overgaard. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis. Radiotherapy and Oncology 100, 22-32 (2011).

V. Mercadante, A.al Hamad, G. Lodi, S. Porter and S. Fedele. Interventions for the management of radiotherapy-induced xerostomia and hyposalivation: A systematic review and meta-analysis. Oral Oncology 66, 64-74 (2017).

A.A. Owosho et al. The role of parotid gland irradiation in the development of severe hyposalivation (xerostomia) after intensity-modulated radiation therapy for head and neck cancer: Temporal patterns, risk factors, and testing the QUANTEC guidelines. Journal of Cranio-Maxillofacial Surgery 45, 595-600 (2017).

E.G. Russi et al. Acute skin toxicity management in head and neck cancer patients treated with radiotherapy and chemotherapy or EGFR inhibitors: Literature review and consensus. Critical Reviews in Oncology / Hematology 96, 167-182 (2015).

P. Blanchard et al. Toward a model-based patient selection strategy for proton therapy: External validation of photon-derived normal tissue complication probability models in a head and neck proton therapy cohort. Radiotherapy and Oncology 121, 381-386 (2016).

K.A. Hutcheson et al. Late Dysphagia after Radiotherapy-Based Treatment of Head and Neck Cancer. Cancer 118, 5793-5799 (2012).

C.M. Nutting et al. Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. Lancet Oncology 12, 127-136 (2011).

S.B. Batth, J.C. Caudell and A.M. Chen. Practical considerations in reducing swallowing dysfunction following concurrent chemoradiotherapy with intensity-modulated radiotherapy for head and neck cancer. Head & Neck DOI 10.1002/HED (2014).

H.R. Mortensen et al. Factors associated with acute and late dysphagia in the DAHANCA 6 & 7 randomized trial with accelerated radiotherapy for head and neck cancer. Acta Oncologica 52, 1535-1524 (2013).

V. Paleri et al. Strategies to reduce long-term postchemoradiation dysphagia in patients with head and neck cancer: An evidence-based review. Head & Neck 36, 431-443 (2014).

L. van der Molen et al. Dysphagia and trismus after concomitant chemo-Intensity-Modulated Radiation Therapy (chemo-IMRT) in advanced head and neck cancer; dose-effect relationships for swallowing and mastication structures. Radiotherapy and Oncology 106, 364-369 (2013).

D. Alterio et al. Radiation-induced acute dysphagia. Strahlentherapie und Onkologie 193, 971-981 (2017).

L. Arribas et al. Nutritional changes in patients with locally advanced head and neck cancer during treatment. Oral Oncology 71, 67-74 (2017).

E. Cereda et al. Nutritional counselling with or without systematic use of oral nutritional supplements in head and neck cancer patients undergoing radiotherapy. Radiotherapy and Oncology, in press (2017).

P. Ravasco et al. Impact of Nutrition on Outcome: A Prospective Randomized Controlled Trial in Patients with Head and Neck Cancer Undergoing Radiotherapy. Head & Neck 27, 659-668 (2005).

S.N. King et al. Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer. Dysphagia 31, 229-251 (2016).

A. Vissink et al. Oral Sequelae of Head and Neck Radiotherapy. Critical Reviews in Oral and Biological Medicine 14, 119-212 (2003).

P. Dirix, S.Nuyts and W. van den Bogaert. Radiation-Induced Xerostomia in Patients with Head and Neck Cancer. Cancer 107, 2525-2534 (2006).

E. Orlandi et al. Salivary Gland. Photon beam and particle radiotherapy: Present and future. Oral Oncology 60, 146-156 (2016).

P.A. Brennan, K.L. Bradley and M. Brands. Intensity-modulated radiotherapy in head and neck cancer – an update for oral and maxillofacial surgeons. British Journal of Oral and Maxillofacial Surgery 55, 770-774 (2017).

V. de Sanctis et al. Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus statements. Critical Reviews in Oncology / Hematology 100, 147-168 (2016).

R. Mazeron et al. Current concepts of management in radiotherapy for head and neck squamous-cell cancer. Oral Oncology 45, 402-408 (2009).

S.A. Bhide and C.M. Nutting. Advances in radiotherapy for head and neck cancer. Oral Oncology 46, 439-441 (2010).

H.Y. Sroussi et al. Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis. Cancer Medicine 6, 2918-2931 (2017).

E. Ivaldi et al. Postoperative radiotherapy (PORT) for early oral cavity cancer (pT1-2, N0-1): A review. Critical Reviews in Oncology / Hematology 143, 67-75 (2019).

D. Nevens et al. Radiotherapy induced dermatitis is a strong predictor for late fibrosis in head and neck cancer. The development of a predictive model for late fibrosis. Radiotherapy and Oncology 122, 212-216 (2017).

J.M. Straub et al. Radiation-induced fibrosis: mechanisms and implications for therapy. Journal of Cancer Research and Clinical Oncology 141, 1985-1994 (2015).

J.J. Tomasek et al. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nature Reviews Molecular Cell Biology 3, 349–363 (2002).

X. Zhao et al. Targeting metabolic dysregulation for fibrosis therapy. Nature Reviews Drug Discovery 19, 57-75 (2020).

B. Wang et al. Advances in pathogenic mechanisms and management of radiation-induced fibrosis. Biomedicine and Pharmacotherapy 121, 109560 (2020).

X. Sun et al. Endothelium-mediated contributions to fibrosis. Seminars in Cell and Developmental Biology 101, 78-86 (2020).

I. Brook. Late side effects of radiation treatment for head and neck cancer. Radiation Oncology Journal 38, 84-92 (2020).

J. Yarnold and M.-C. Vozenin Brotons. Pathogenetic mechanisms in radiation ﬁbrosis. Radiotherapy and Oncology 97, 149–161 (2010).

J.W. Denham and M. Hauer-Jensen. The radiotherapeutic injury – a complex ‘wound’. Radiotherapy and Oncology 63, 129–145 (2002).

J. Castelli et al. Adaptive radiotherapy for head and neck cancer. Acta Oncologica 57, 1284-1292 (2018).

M.R. Borrelli et al. Radiation-induced skin fibrosis: pathogenesis, current treatment options, and emerging therapeutics. Annals of Plastic Surgery 83, S59–S64 (2019).

M.D. Davidson, J.A. Burdick and R.G. Wells. Engineered Biomaterial Platforms to Study Fibrosis. Advanced Healthcare Materials 9, 901682 (2020).

D. Pohlers et al. TGF-β and fibrosis in different organs — molecular pathway imprints. Biochimica et Biophysica Acta 1792, 746-756 (2009).

V.J. Müller et al. Change of saliva composition with radiotherapy. Archives of Oral Biology 106, 104480 (2019).

S. Lee and C. Thiele. Factors associated with free ﬂap complications after head and neck reconstruction and the molecular basis of ﬁbrotic tissue rearrangement in pre-irradiated soft tissue. Journal of Oral and Maxillofacial Surgery 68, 2169-2178 (2010).